Program

SUNDAY, JUNE 11

08:00 - 18:30

Registration: ICPVR 2017 Secretariat (Convention Center area - Tropical Ecoresort Hotel)

 

A Meeting Room (20 people capacity), close to the Secretariat in Tropical Ecoresort, is available for small side meetings during the conference (at no cost). Please let us know if you are interested and make your reservation.

 

09:00 – 13:00

MORNING PRE-MEETING COURSES (16th floor - Wyndham Garden Hotel)

 

Course 1: Parasite biology, animal models and imaging advances (Rouxinol Room)
Organizers: Rogério Amino (France), Mary Galinski (USA) and Letusa Albrecht (Brazil)

Course 2: Conducting epidemiological studies (Bem-te-vi Room)
Organizers: Ivo Mueller (Australia/France), Ingrid Felger (Switzerland) and Wuelton Monteiro (Brazil)

Course 3: Conducting clinical trials (Uirapuru Room)
Organizers:  Quique Bassat (Spain), Ric Price (Australia/UK) and André Siqueira (Brazil)

13:00 - 14:30

LUNCH (lunch will be served for participants at the Wyndham Garden's restaurant floor level)

14:30 - 18:00

AFTERNOON PRE-MEETING COURSES (16th floor - Wyndham Garden Hotel)

Course 4: Understanding omics data and modelling studies (Bem-te-vi Room)
Organizers: Jessica Kissinger (USA), Michael White (UK) and Gabriela Gomes (UK)

Course 5: Programatic challenges to vivax malaria elimination (Rouxinol Room)
Organizers: Kevin Baird (Indonesia), Marcelo Ferreira (Brazil), Paola Marchesini (Brazil)

Course 6: Scientific publishing (Uirapuru Room)
Organizers: Marcel Hommel (UK) and Judith Recht (Brazil)

 

Guided visits to a limited number of people to the Tropical Medicine Foundation Dr. Heitor Vieira Dourado will happen during the morning. A van will be available in the lobby of Wyndham Garden at 10am (local contact will be Mr. Erick Frota). If you are interested please contact Mrs. Ana Paula Souza (icpvr2017@gmail.com).

 

19:30 - 21:00

OPENING CEREMONY (Convention Center Area - Tropical Ecoresort Hotel - Rio Solimões Ballroom)

Welcoming Words

#timetogoforvivax - Documentary Film

Grassi & Feletti Opening Lecture
Chair: Marcus Lacerda (Brazil)

Kevin Baird (Indonesia)
After seventy years of dormancy, Plasmodium vivax research awakens

 

21:00 - 23:00    

RECEPTION - TYPICAL BRAZILIAN JUNE  PARTY (FESTA JUNINA OR FESTA DE SÃO JOÃO) (Convention Center Area - Tropical Ecoresort Hotel - Rio Negro Ballroom) - Typical food and drinks will be served

 


MONDAY, JUNE 12
 

All the scientific activities from Monday to Wednesday will take place at the Convention Center Area - Tropical Ecoresort Hotel. Please wear your badge to gain access.

 

9:00 - 11:00 

TOPIC 1: TACKLING THE HYPNOZOITE AND RELAPSE
Chairs: Dominique Mazier (France) and Cristiana Brito (Brazil) 

Steven Maher (USA)
Advances in the search for new drugs that target hypnozoites

Sebastian Mikolajczak (USA)
P. vivax: liver stage development and hypnozoite persistence in humanized mouse liver
 

Oral presentations (15 min) from abstracts

Melisa Gualdrón-López (Spain)                       
Plasma-derived exosomes from Plasmodium vivax infected liver-chimeric (huHep) FRG mice as novel biomarkers of liver infection

Roger Cubi/Shruthi Vembar (France)
Laser capture microdissection enables transcriptomic analysis of dividing and quiescent liver stages of Plasmodium relapsing species

Chester Joyner (USA)
Malaria relapses expand B-cell memory that provides strain-specific protection against reinfection

 

Turbo talks (5 min) from abstracts

Anne Marie Zeeman (Netherlands)
The transcriptome of dormant and developing liver stages of P. cynomolgi

Alison Roth (USA)
Engineering hepatic microenvironments for efficient and predictive pre-clinical Plasmodium vivax liver stage assays

Jessica Lin (USA)
Whole genome analysis of successive Plasmodium vivax relapses in Cambodia reveals polyclonal infections that are genetically related

Dennis Shanks (Australia)
Hemolysis as a signal to initiate Plasmodium vivax relapse

 

11:00 - 11:30 

COFFEE BREAK


11:30 - 13:30 

TOPIC 2: ACHIEVING UNIVERSAL ACCESS TO SAFE AND EFFECTIVE RADICAL CURE 
Chairs: Cindy Chu (Thailand) and Germana Bancone (Thailand)


Lucio Luzzatto (Tanzania) 
G6PD deficiency and acute haemolytic anaemia caused by primaquine and other agents

Kevin Baird (Indonesia) 
How to treat P. vivax infection where G6PD deficiency is common

 

Oral presentations (15 min) from abstracts

Raul Chuquiyauri (Peru)
Tafenoquine for radical cure of Plasmodium vivax malaria: a multicentre, randomised, double-blind, placebo-controlled phase III trial (DETECTIVE)

Marcus Lacerda (Brazil)
Tafenoquine for radical cure of Plasmodium vivax malaria: a randomized, double-blind, double-dummy, comparative, multicenter Phase III study (GATHER)

Cindy Chu (Thailand)
Hemolysis in G6PD heterozygous females treated with primaquine for Plasmodium vivax malaria: a nested cohort in a trial of radical curative regimens
 

Turbo talks (5 min) from abstracts

Annette Erhart (Belgium)
P. vivax morbidity after radical treatment: a 2-year cohort studies in Central Vietnam

Robert Commons (Australia)
The WWARN pooled analysis of chloroquine dosing

Chansuda Wongsrichanalai (Thailand)
Primaquine radical therapy for P. vivax malaria: different scenarios of policy and use across endemic countries

 

13:30 - 15:00 

POSTER SESSION 1 (Rio Negro Ballroom - lunch boxes will be served) - all posters will be displayed from Monday to Wednesday following the abstract code order

 

15:00 - 17:00

TOPIC 3: NOVEL INSIGHTS INTO PARASITE BIOLOGY   
Chairs: Luzia Carvalho (Brazil)


Wai-Hong Tham (Australia) 
Malaria parasite invasion, versatile structural scaffolds and alternate erythrocyte receptors

Adeline Chua (New Zealand)
Reestablishing Plasmodium cynomolgi continuous culture

 

Oral presentations (15 min) from abstracts

Benoit Malleret (Singapore)
CD98 is a Plasmodium vivax receptor for human reticulocytes

Usheer Kanjee (USA)
Functional analysis of red blood cell determinants of Plasmodium vivax invasion

Marcelo Brito (Brazil)
Dyserythropoiesis during anemia related to acute vivax malaria: morphological and transcriptional profile


Turbo talks (5 min) from abstracts

Luis Carlos Salazar-Alvarez (Brazil)
Rosetting ability and adhesion of P. vivax gametocytes to endothelial cells and their influence on infectivity in Anopheles aquasalis

Nicanor Obaldia (Panamá)
The bone marrow as a major hub for P. vivax infection

Wanlapa Roobsoong (Thailand)
PvDBP mutations and copy numbers of Plasmodium vivax from Duffy negatives: association with erythrocyte invasion and clinical diseases

 

17:00 - 17:30

TEA BREAK
 

17:30 - 19:30

TOPIC 4: SYSTEMS BIOLOGY
Chairs: Jessica Kissinger (USA)


Elizabeth Winzeler (USA) 
Whole genome analysis


Mark Styczynski (USA) 
Integrative systems biology of a rhesus macaque model of P. vivax malaria

 

Oral presentations (15 min) from abstracts

Rosa Santana (Brazil)
Anopheles darlingi and Anopheles aquasalis transcriptome during Plasmodium vivax infection

Alison Roth (USA)
Discovery of infectivity genes in Plasmodium vivax sporozoites

Luiz Gardinassi (USA)
Metabolic signatures of distinct clinical outcomes of a Plasmodium vivax controlled human malaria infection


Turbo-talks (5 min) from abstracts

Cristina Ariani (UK)
SPOTmalaria: a global collaborative platform to survey the major human malaria parasites using genomic data

Karan Uppal (USA)
Metabolomics reveals membrane lipids, aspartate/asparagine and nucleotide metabolism pathway differences associated with chloroquine resistance in Plasmodium vivax malaria

Sonia Agrawal (USA)
Whole genome sequencing of Plasmodium vivax from the China-Myanmar border using whole genome sequence capture

 

Free evening. Monday is Brazilian Valentine's day and most restaurants are overbooked. Make your reservation soon! The president of the organizing committee suggests the following restaurants: Banzeiro, Amazônico, Choupana, Moquem (typical local food, specially fish), Cachaçaria do Dedé, Cent Beer, Sindicato (typical Brazilian bar), Gaúcho's, Búfalo, Axerito (typical Brazilian steak house), Village, Barollo, Precioska, Batelão Brasserie (international food), Alentejo (Portuguese food), Domus, Crepe Bistro (French food), Suzuran, Miako, Umê (Japanese food), Dom Domenico, Chef Tony, Trattoria da Margot, Casa do Mário (Italian food).

 


TUESDAY, JUNE 13
 

9:00 - 11:00 

TOPIC 5: EPIDEMIOLOGY AND SURVEILLANCE
Chairs: Chris Drakeley (UK) and Dionicia Gamboa (Peru)  


Ric Price (Australia/UK) 
Delayed mortality following recurrent P. vivax infection

Joe Vinetz (USA) 
Mechanisms of resilient malaria in the Peruvian Amazon
 

Oral presentations (15 min) from abstracts

Fitsum Tadesse (Netherlands)
The shape of the iceberg: quantification of submicroscopic P. falciparum and P. vivax parasitaemia and gametocytemia in five low endemic settings in Ethiopia

Jane Carlton (USA)
The hidden burden of Plasmodium vivax in India: sub microscopic parasites and asymptomatic infections complicate vivax elimination

Priscila Rodrigues (Brazil)
Origin and introduction routes of Plasmodium vivax in the American Continent


Turbo talks (5 min) from abstracts

Ghyslaine Bruna (Cameroon)
Molecular evidence of Plasmodium vivax Infection in Duffy-Negative symptomatic autochthones individuals from West Cameroon

Fabián Sáenz (Ecuador)
Presence of P. vivax infections in Duffy-negative individuals in a low endemic area of the Pacific Coast of South America

Anielle Pina (Brazil)
Malaria in Rio de Janeiro State Brazil

 

11:00 - 11:30

COFFEE BREAK

 

11:30 - 13:30

TOPIC 6: UNDERSTANDING, MAPPING AND NOVEL INTERVENTIONS IN TRANSMISSION
Chairs: Norma Padilla (Guatemala) and Paulo Pimenta (Brazil)


Rhoel Dinglasan (USA) 
Dissecting P. vivax transmission biology through comparative omics, chemical probes and molecular tools
 

Kevin Kobylinski (Thailand) 
Ivermectin mass drug administration for malaria elimination

 

Oral presentations (15 min) from abstracts

Mathilde Gendrin (French Guiana)
The effect of the mosquito microbiota on malaria transmission

James McCarthy (Australia)
High level human to mosquito transmission of Plasmodium vivax during CHMI

Marta Moreno (Peru)
Infectivity of Anopheles darlingi with symptomatic and asymptomatic Plasmodium vivax infections in the Peruvian Amazon


Turbo talks (5 min) from abstracts

Paulo Pimenta (Brazil)
Use of ivermectin for transmission blocking of Plasmodium vivax in Anopheles aquasalis and Anopheles darlingi

Gissella Vásquez (Peru)
Production of Plasmodium vivax sporozoites in laboratory-bred Anopheles darlingi mosquitoes

Muzamil Hamid (Sudan)
Molecular and morphological identification of suspected P. vivax malaria vectors in Sudan

 

13:30 - 15:00 

POSTER SESSION 2 (Rio Negro Ballroom - lunch boxes will be served) - all posters will be displayed from Monday to Wednesday following the abstract code order

 

15:00 - 17:00 

TOPIC 7: IMMUNITY, PATHOGENESIS, VACCINE DISCOVERY AND DEVELOPMENT 
Chairs: Chetan Chitnis (France)


Christopher King (USA) 
Characterization of functional antibodies to malaria host/parasite interactions utilizing human monoclonal antibodies
 

Arturo Reyes-Sandoval (UK) 
A P. vivax pre-erythrocytic vaccine using virus-like particles: towards clinical development

 

Oral presentations (15 min) from abstracts

Noah Sather (USA)
Exploring the potential of vaccine-elicited antibodies against the pre-erythrocytic stages of P. vivax malaria to bolster eradication efforts

Camila Barbosa (Brazil)
Elucidation of the HLA class I antigen-presenting pathway in P. vivax infected reticulocytes

Damian Oyong (Australia)
Does complement protection come at a cost? Role of complement-fixing antibodies in the pathogenesis of severe malaria anaemia of P. vivax infection


Turbo talks (5 min) from abstracts

Steven Kho (Australia)
Platelets kill circulating Plasmodium parasites in human malaria: greater killing of circulating P. vivax than P. falciparum or P. malariae

Stephanie Yanow (Canada)
Antibodies to Plasmodium vivax PvDBP recognize VAR2CSA and block adhesion of P. falciparum-infected red cells to chondroitin sulphate A

Zoe Shih-Jung Liu (Australia)
Defining antibody kinetics and longevity to 40 Plasmodium vivax antigens in individuals from western Thailand

 

17:00 - 17:30

TEA BREAK

 

17:30 - 18:00

TOPIC 8: LATE BREAKERS TURBO TALKS
Chairs: Lise Musset (French Guiana) and Takafumi Tsuboi (Japan)

Daniel Bargieri (Brazil)
Ookluc, a new tool to study Plasmodium transmission

Lilia Gonzalez (Mexico)
Plasmodium vivax genetic selection and further adaptations to sympatric vector species in southern Mexico

Gabriel Rangel (USA)
Enhanced ex vivo Plasmodium vivax intraerythrocytic maturation from cryopreserved isolates for highly sensitive antimalarial susceptibility assays

Camila França (Australia)
Naturally-acquired antibodies to recombinant P. vivax antigens: identification of potential novel vaccine candidates

Andre Siqueira (Brazil)
Serological Screening and Treatment (SSAT) as adjuvant in an intensive P. vivax elimination strategy in Southern Brazil, 1980s

Miriam Diaz-Varela (Spain)
Proteomic analysis of human reticulocyte-derived exosomes and studies of their antigen presenting capacity

 

20:00 - 21:00

Badges of the conference will need to be presented at the foyer of the Opera House for entrance.
No strict dress code, but please avoid the flip flops.

VIVACE - AMAZONAS GUITAR ORQUESTRA (Opera House) - buses will depart from the hotel from 19:00-19:30

 

21:00-22:00

RECEPTION (External balconies of the Opera House) - Food and drinks will be served - buses will depart to the hotel from 22:00-22:30

 


WEDNESDAY, JUNE 14


9:00 - 11:00 

TOPIC 9: ARE CURRENT CONTROL STRATEGIES AIMED AT P. VIVAX WORKING?
Chairs: Qin Cheng (Australia) and Richard Maude (Thailand) 


Ingrid Felger (Switzerland) 
Limitations of nucleic acid amplification tests for diagnosis of P. vivax in community surveys and possible solutions

Iveth Gonzalez (Switzerland) 
Diagnosis for P. vivax malaria: status and needs

 

Oral presentations (15 min) from abstracts

Anna Rosanas-Urgell (Belgium)
Loop-mediated isothermal amplification for asymptomatic malaria diagnosis in the Peruvian Amazon: technical performance and pilot implementation in challenging field settings

David Sebba (USA)
Performance testing of quantitative G6PD point-of-care test in Thailand

Kevin Baird (Indonesia)
Epidemiology and diagnosis of G6PD deficiency in heterozygous females


Turbo talks (5 min) from abstracts

Nathália Siqueira (Brazil)
Mixed infections detected by nested PCR from archival thick blood films

Angela Devine (Thailand)
Using G6PD tests to enable the safe treatment of Plasmodium vivax infections with primaquine on the Thailand-Myanmar border: a cost-effectiveness analysis

Mariusz Wojnarski (Thailand)
Lessons learned from deployment of primaquine (PQ) in G6PD normal and deficient volunteers in pilot malaria elimination study in the military cohort in Cambodia

 

 

11:00 - 11:30

COFFEE BREAK

 

11:30 - 13:00

TOPIC 10: TOWARDS ELIMINATION OF P. VIVAX MALARIA
Chair: Ivo Müeller (Australia/France) and André Siqueira (Brazil) 


Brice Campo (Switzerland) 
MMV P. vivax liver stage strategy and advances on projects and countries working effectively towards elimination
 

Scott Miller (USA) 
Filling the toolbox for P. vivax elimination

 

Oral presentations (15 min) from abstracts

Wang Nguitragoo (Thailand)
Substantial Population Structure of Plasmodium vivax in Thailand facilitates identification of the sources of residual transmission

Zuleima Pava (Australia)
Longitudinal molecular analysis of P. vivax and P. falciparum infections before and after implementation of Artemisinin-Based Combination Therapy in Papua, Indonesia

Pablo Fontoura (Brazil)
Prospects for residual malaria elimination in rural Brazilian Amazon: strategy of reactive case detection for surveillance Plasmodium vivax in reservoir hosts

 

13:00 - 14:00 

POSTER SESSION 3 (Rio Negro Ballroom - lunch boxes will be served) - all posters will be displayed from Monday to Wednesday following the abstract code order

 

14:00 - 15:00

TOPIC 11: IS MODELLING ACCELERATING ELIMINATION?
Chairs: Gabriela Gomes (UK) and Miles Davenport (Australia) 


Michael White (UK) 
Expanded control and elimination of P. vivax in Papua New Guinea: a mathematical modelling study

 

Oral presentations (15 min) from abstracts

Gonzalo Domingo (USA)
Using modeled P. vivax prevalence data to estimate the market size for glucose-6-phosphate dehydrogenase (G6PD) deficiency tests in order to support decision making on service delivery models

James Watson (Thailand)
Modelling primaquine-induced haemolysis in G6PD deficiency

 

Turbo talk (5 min) from abstract

Rodrigo Corder (Brazil)
Mathematical modelling of malaria transmission considering heterogeneity in exposure and susceptibility of hosts

 

15:00 - 15:30

TEA BREAK

 

15:30 - 17:00

CLOSING CEREMONY

Krotoski Closing Lecture
Chair: Hernando del Portillo (Spain)

Nick White (UK/Thailand)
Relapse

Welcoming words to ICPVR 2019
Chetan Chitnis (France)

 

17:00 - ....

SUNSET VIEW AT THE TRADITIONAL SWIMMING POOL VIVAX PARTY (Wyndham Garden)

 

Program updated June 8, 2017