Program

SUNDAY, JUNE 11

09:00 - 18:30

Registration in the Secretariat of the ICPVR 2017 (Convention Center area - Tropical Ecoresort Hotel)


09:00 – 13:30

MORNING PRE-MEETING COURSES (16th floor - Wyndham Garden Hotel)

 

Course 1: Parasite biology, animal models and imaging advances (Room TBD)
Organizers: Rogério Amino (France), Mary Galinski (USA) and Letusa Albrecht (Brazil)

Course 2: Conducting epidemiological studies (Room TBD)
Organizers: Ivo Mueller (Australia/France), Ingrid Felger (Switzerland) and Wuelton Monteiro (Brazil)

Course 3: Conducting clinical trials (Room TBD)
Organizers:  Quique Bassat (Spain), Ric Price (Australia/UK) and André Siqueira (Brazil)

 

13:30 - 14:30

LUNCH (lunch boxes will be served for participants)

 

14:30 - 18:00

AFTERNOON PRE-MEETING COURSES (16th floor - Wyndham Garden Hotel)

Course 4: Understanding omics data and modelling studies (Room TBD)
Organizers: Jessica Kissinger (USA), Michael White (UK) and Gabriela Gomes (UK)

Course 5: Programatic challenges to vivax malaria elimination (Room TBD)
Organizers: Kevin Baird (Indonesia), Marcelo Ferreira (Brazil), Paola Marchesini (Brazil)

Course 6: Scientific publishing (Room TBD)
Organizers: Marcel Hommel (UK) and Judith Recht (Brazil)

 

Guided visits to a limited number of people to the Tropical Medicine Foundation Dr. Heitor Vieira Dourado will happen during the morning and during the afternoon. Buses will be available from/to the hotel. If you are interested please contact Mrs. Ana Paula Souza (icpvr2017@gmail.com).

 

19:30 - 21:00

OPENING CEREMONY (Convention Center Area - Tropical Ecoresort Hotel - Rio Solimões Ballroom)

Welcoming Words
Marcus Lacerda (Brazil)

Grassi & Feletti Opening Lecture
Chair: Marcus Lacerda (Brazil)

Pedro Alonso (Switzerland)
P. vivax malaria research in the context of elimination

 

21:00 - 23:00    

RECEPTION - TYPICAL BRAZILIAN JUNE  PARTY (Convention Center Area - Tropical Ecoresort Hotel - Rio Negro Ballroom) - Typical food and drinks will be served

 


MONDAY, JUNE 12
 

All the scientific activities from Monday to Wednesday will take place at the Convention Center Area - Tropical Ecoresort Hotel. Badges are mandatory to access all the activities.

 

9:00 - 11:00 

TOPIC 1: TACKLING THE HYPNOZOITE AND RELAPSE
Chairs: Dominique Mazier (France) and Cristiana Brito (Brazil) 

Dennis Kyle (USA)

Advances in the search for new drugs that target hyonozoites

Sebastien Mikolajczak (USA)

P. vivax: liver stage development and hypnozoite persistence in humanized mouse liver
 

Oral presentations (15 min) from abstracts

Roger Cubi and Shruthi S. Vembar (France)

Laser capture microdissection enables transcriptomic analysis of dividing and quiescent liver stages of Plasmodium relapsing species

Chester J. Joyner (USA)

Malaria relapses expand B-cell memory that provides strain-specific protection against reinfection

Melisa Gualdrón-López (Spain)                       

Plasma-derived exosomes from Plasmodium vivax infected liver-chimeric (huHep) FRG mice as novel biomarkers of liver infection

 

Turbo talks (5 min) from abstracts

Annemarie Voorberg-van der Wel (Netherlands)

The transcriptome of dormant and developing liver stages of P. cynomolgi

Steven P. Maher (USA)

Engineering hepatic microenvironments for efficient and predictive pre-clinical Plasmodium vivax liver stage assays

Nicholas F. Brazeau (USA)

Whole genome analysis of successive Plasmodium vivax relapses in Cambodia reveals polyclonal infections that are genetically related

 

11:00 - 11:30 

COFFEE BREAK


11:30 - 13:30 

 

TOPIC 2: ACHIEVING UNIVERSAL ACCESS TO SAFE AND EFFECTIVE RADICAL CURE 
Chairs: Cindy Chu (Thailand) and Germana Bancone (Thailand)


Kevin Baird (Indonesia) 
How to treat P. vivax infection where G6PD deficiency is common

Lucio Luzzatto (Tanzania) 
G6PD deficiency and acute haemolytic anaemia caused by primaquine and other agents

 

Oral presentations (15 min) from abstracts

Marcus Lacerda (Brazil)

Tafenoquine for radical cure of Plasmodium vivax malaria: a randomized, double-blind, double-dummy, comparative, multicenter Phase III study (GATHER)

Alejandro Llanos-Cuentas (Peru)

Tafenoquine for radical cure of Plasmodium vivax malaria: a multicentre, randomised, double-blind, placebo-controlled phase III trial (DETECTIVE)

Cindy Chu (Thailand)

Hemolysis in G6PD heterozygous females treated with primaquine for Plasmodium vivax malaria: a nested cohort in a trial of radical curative regimens
 

Turbo talks (5 min) from abstracts

Annette Erhart (Belgium)

P. vivax mordidity after radical treatment: a 2-year cohort studies in Central Vietnam

Robert Commons (Australia)

The WWARN pooled analysis of chloroquine dosing

One more TBA

 

13:30 - 15:00 

POSTER SESSION 1 (Rio Negro Ballroom - lunch boxes will be served)

 

15:00 - 17:00

TOPIC 3: NOVEL INSIGHTS INTO PARASITE BIOLOGY   
Chairs: Bruce Russel (New Zealand) and Luzia Carvalho (Brazil)


Wai-Hong Tham (Australia) 
Malaria parasite invasion, versatile structural scaffolds and alternate erythrocyte receptors

Peter Zimmerman (USA) 

Plasmodium vivax isolates from Madagascar: Sample collection to in vitro culture

 

Oral presentations (15 min) from abstracts

Benoit Malleret (Singapore)

CD98 is a Plasmodium vivax receptor for human reticulocytes

Usheer Kanjee (USA)

Functional analysis of red blood cell determinants of Plasmodium vivax invasion

Marcelo Brito (Brazil)

Dyserythropoiesis during anemia related to acute vivax malaria: morphological and transcriptional profile


Turbo talks (5 min) from abstracts

Luis Carlos Salazar-Alvarez (Brazil)

Rosetting ability and adhesion of P. vivax gametocytes to endothelial cells and their influence on infectivity in Anopheles aquasalis

Nicanor Obaldia (Panamá)

The bone marrow as a major hub for P. vivax infection

Eugenia Lo (USA)

PvDBP mutations and copy numbers of Plasmodium vivax from Duffy negatives: association with erythrocyte invasion and clinical diseases

Bruce Russel

Continuous culture of P. cynomolgi

 

17:00 - 17:30

TEA BREAK
 

17:30 - 19:30

TOPIC 4: SYSTEMS BIOLOGY
Chairs: Zbynek Bozdech (Singapore) and Jessica Kissinger (USA) 


Elizabeth Winzeler (USA) 
Whole genome analysis


Mark Styczynski (USA) 
Integrative systems biology of a rhesus macaque model of P. vivax malaria

 

Oral presentations (15 min) from abstracts

Rosa Santana (Brazil)

Anopheles darlingi and Anopheles aquasalis transcriptome during Plasmodium vivax infection

Alison Roth (USA)

Discovery of infectivity genes in Plasmodium vivax sporozoites

Luiz Gardinassi (USA)

Amino acid metabolism is associated with the transcriptional module of T cell activation and co-stimulation in humans experimentally infected with Plasmodium vivax


Turbo-talks (5 min) from abstracts

Cristina Ariani (UK)

SPOTmalaria: a global collaborative platform to survey the major human malaria parasites using genomic data

Karan Uppal (USA)

Metabolomics reveals membrane lipids, aspartate/asparagine and nucleotide metabolism pathway differences associated with chloroquine resistance in Plasmodium vivax malaria

Sonia Agrawal (USA)

Whole genome sequencing of Plasmodium vivax from the China-Myanmar border using whole genome sequence capture

 


TUESDAY, JUNE 13
 

9:00 - 11:00 

TOPIC 5: EPIDEMIOLOGY AND SURVEILLANCE
Chairs: Chris Drakeley (UK) and Dionicia Gamboa (Peru)  


Ric Price (Australia/UK) 
Delayed mortality following recurrent P. vivax infection
 

Joe Vinetz (USA) 
Mechanisms of resilient malaria in the Peruvian Amazon

 

Oral presentations (15 min) from abstracts

Fitsum Tadesse (Netherlands)

The shape of the iceberg: quantification of submicroscopic P. falciparum and P. vivax parasitaemia and gametocytemia in five low endemic settings in Ethiopia

Alex Eapen (India)

The hidden burden of Plasmodium vivax in India: sub microscopic parasites and asymptomatic infections complicate vivax elimination

Priscila Rodrigues (Brazil)

Origin and introduction routes of Plasmodium vivax in the American Continent


Turbo talks (5 min) from abstracts

Ghyslaine Bruna (Cameroon)

Molecular evidence of Plasmodium vivax Infection in Duffy-Negative symptomatic autochthones individuals from West Cameroon

Fabián Sáenz (Ecuador)

Presence of P. vivax infections in Duffy-negative individuals in a low endemic area of the Pacific Coast of South America

One more TBA

 

11:00 - 11:30

COFFEE BREAK

 

11:30 - 13:30

TOPIC 6: UNDERSTANDING, MAPPING AND NOVEL INTERVENTIONS IN TRANSMISSION
Chairs: Norma Padilla (Guatemala) and Paulo Pimenta (Brazil)


Rhoel Dinglasan (USA) 
Dissecting P. vivax transmission biology through comparative omics, chemical probes and molecular tools
 

Kevin Kobylinski (Thailand) 
Ivermectin mass drug administration for malaria elimination

 

Oral presentations (15 min) from abstracts

Mathilde Gendrin (French Guiana)

The effect of the mosquito microbiota on malaria transmission

Katharine Collins (Australia)

High level human to mosquito transmission of Plasmodium vivax during CHMI

Marta Moreno (Peru)

Infectivity of Anopheles darlingi with symptomatic and asymptomatic Plasmodium vivax infections in the Peruvian Amazon


Turbo talks (5 min) from abstracts

Paulo Pimenta (Brazil)

Use of ivermectin for transmission blocking of Plasmodium vivax in Anopheles aquasalis and Anopheles darlingi

Gissella Vásquez (Peru)

Production of Plasmodium vivax sporozoites in laboratory-bred Anopheles darlingi mosquitoes

Muzamil Hamid (Sudan)

Molecular and morphological identification of suspected P. vivax malaria vectors in Sudan

 

13:30 - 15:00 

POSTER SESSION 2 (Rio Negro Ballroom - lunch boxes will be served)

 

15:00 - 17:00 

TOPIC 7: IMMUNITY, PATHOGENESIS, VACCINE DISCOVERY AND DEVELOPMENT 
Chairs: Chetan Chitnis (France) and Myriam Arevalo (Colombia) 


Christopher King (USA) 
Characterization of functional antibodies to malaria host/parasite interactions utilizing human monoclonal antibodies
 

Arturo Reyes Sandoval (UK) 
A P. vivax pre-erythrocytic vaccine using virus-like particles: towards clinical development

 

Oral presentations (15 min) from abstracts

David Sather (USA)

Exploring the potential of vaccine-elicited antibodies against the pre-erythrocytic stages of P. vivax malaria to bolster eradication efforts

Camila Barbosa (Brazil)

Elucidation of the HLA class I antigen-presenting pathway in P. vivax infected reticulocytes

Damian Oyong

Does complement protection comes at a cost? Role of complement-fixing antibodies in the pathogenesis of severe malaria anaemia of P. vivax infection


Turbo talks (5 min) from abstracts

Steven Kho (Australia)

Platelets kill circulating Plasmodium parasites in human malaria: greater killing of circulating P. vivax than P. falciparum or P. malariae

Stephanie Yanow (Canada)

Antibodies to Plasmodium vivax PvDBP recognize VAR2CSA and block adhesion of P. falciparum-infected red cells to chondroitin sulphate A

Zoe Shih-Jung Liu (Australia)

Defining antibody kinetics and longevity to 40 Plasmodium vivax antigens in individuals from western Thailand

 

17:00 - 17:30

TEA BREAK

 

17:30 - 18:00

TOPIC 8: LATE BREAKERS
Chairs: Lise Musset (French Guiana) and Takafumi Tsuboi (Japan)

Turbo talks (6/5 min) from abstracts (TBA)

 

20:00 - 21:00

Badges of the conference will need to be presented at the foyer of the Opera House for entrance

AMAZONAS GUITAR ORQUESTRA (Opera House) - buses will depart from the hotel from 19:00-19:30

21:00-22:00

RECEPTION (External balconies of the Opera House) - Food and drinks will be served - buses will depart to the hotel from 22:00-22:30

 


WEDNESDAY, JUNE 14


9:00 - 11:00 

TOPIC 9: ARE CURRENT CONTROL STRATEGIES AIMED AT P. VIVAX WORKING?
Chairs: Qin Cheng (Australia) and Richard Maude (Thailand) 


Ingrid Felger (Switzerland) 
Limitations of nucleic acid amplification tests for diagnosis of P. vivax in community surveys and possible solutions

Iveth Gonzalez (Switzerland) 
Diagnosis for P. vivax malaria: status and needs

 

Oral presentations (15 min) from abstracts

Elisa Serra-Casas (Belgium)

Loop-mediated isothermal amplification for asymptomatic malaria diagnosis in the Peruvian Amazon: technical performance and pilot implementation in challenging field settings

David Sebba (USA)

Performance testing of quantitative G6PD Point-of-Care test in Thailand

Ari Satyagraha (Indonesia)

Epidemiology and diagnosis of G6PD deficiency in heterozygous females


Turbo talks (5 min) from abstracts

Nathália Siqueira (Brazil)

Mixed infections detected by nested PCR from archival thick blood films

Angela Devine (Thailand)

Using G6PD tests to enable the safe treatment of Plasmodium vivax infections with primaquine on the Thailand-Myanmar border: a cost-effectiveness analysis

Bahita Assefa (Ethiopia)

Assessment of common Glucose-6-Phosphate dehydrogenase (G6PD) deficiency allelic types in Ethiopia

 

11:00 - 11:30

COFFEE BREAK

 

11:30 - 13:00

TOPIC 10: TOWARDS ELIMINATION OF P. VIVAX MALARIA
Chair: Ivo Müeller (Australia/France) and André Siqueira (Brazil) 


Brice Campo (Switzerland) 
MMV P. vivax liver stage strategy and advances on projects and countries working effectively towards elimination
 

Scott Miller (USA) 
Filling the toolbox for P. vivax elimination

 

Oral presentations (15 min) from abstracts

Liwang Cui (Thailand)

Substantial Population Structure of Plasmodium vivax in Thailand facilitates identification of the sources of residual transmission

Zuleima Pava (Australia)

Longitudinal molecular analysis of P. vivax and P. falciparum infections before and after implementation of Artemisinin-Based Combination Therapy in Papua, Indonesia

Pablo Fontoura (Brazil)

Prospects for residual malaria elimination in rural Brazilian Amazon: strategy of reactive case detection for surveillance Plasmodium vivax in reservoir hosts

 

13:00 - 14:00 

POSTER SESSION 3 (Rio Negro Ballroom - lunch boxes will be served)

 

14:00 - 15:00

TOPIC 11: IS MODELLING ACCELERATING ELIMINATION?                                                                                                                                                                                                                                                                                                                                                                                                                      Chairs: Gabriela Gomes (UK) and Miles Davenport (Australia) 


Michael White (UK) 
Expanded control and elimination of P. vivax in Papua New Guinea: a mathematical modelling study

 

Oral presentations (15 min) from abstracts

Michael Kalnoky (USA)

Using modeled P. vivax prevalence data to estimate the market size for glucose-6-phosphate dehydrogenase (G6PD) deficiency tests in order to support decision making on service delivery models

James Watson (Thailand)

Modelling primaquine-induced haemolysis in G6PD deficiency

 

Turbo talk (5 min) from abstract

Elizabeth Trippe (USA)

Application of consensus differential network analysis to explore host response to Plasmodium cynomolgi infection

 

15:00 - 15:30

TEA BREAK

 

15:30 - 17:00

CLOSING CEREMONY

Krotoski Closing Lecture
Chair: Hernando del Portillo (Spain)

Nick White (UK/Thailand)
Relapse

Welcoming words to ICPVR 2019
Chetan Chitnis (France)

 

17:00 - ....

SUNSET VIEW AT THE TRADITIONAL SWIMMING POOL VIVAX PARTY (Wyndham Garden)

 

Program updated May 23, 2017